
︎ Time in Lisbon (WEST)
8:30
10:00
10:30
11:00
Jacky G. Goetz, PhD
INSERM - National Institute of Health and Medical Research
11:30
12:00
Keynote Lecture
13:00
14:30
MCP-1-CCR2/4 axis plays a crucial role in astrocyte-breast cancer interactions facilitating
brain metastasis
15:00
Yasuyuki Fujita, PhD
Graduate School of Medicine, Kyoto University
15:30
Neuron-glial interactions in health and disease: from cognition to cancer
Michelle Monje, MD, PhD
Stanford University
Howard Hughes Medical Institute
16:00
Delta One T cells: a new adoptive cell therapy for cancer
Bruno Silva-Santos, PhD
Faculdade de Medicina da Universidade de Lisboa
Instituto de Medicina Molecular (iMM)
16:30
17:00
NetworkingMeet the speaker
Meet the invited speakers in small groups and discuss your questions on research or career in 10 minute slots.
18:00 & 18.30
Explore the Champalimaud Centre for the Unknown in a guided tour to the building, including a visit to the labs and stories about the Champalimaud Research culture.
8:30
Registration
10:00
Opening Remarks
10:30
11:00
Intravascular forces shape tumor metastasis
Intravascular forces shape tumor metastasis
Jacky G. Goetz, PhD
INSERM - National Institute of Health and Medical Research
11:30
Coffee Break
12:00
Keynote Lecture
13:00
Lunch
14:30
MCP-1-CCR2/4 axis plays a crucial role in astrocyte-breast cancer interactions facilitating
brain metastasis
Sahar Israeli Dangoor, PhD Candidate
Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University
Department of Physiology and Pharmacology, Sackler Faculty of Medicine, Tel Aviv University
14:45
Uncovering the mechanisms leading to Basal Cell Carcinoma initiation
Sara Canato, PhD
Postdoc @Champalimaud Foundation
Postdoc @Champalimaud Foundation
15:00
Yasuyuki Fujita, PhD
Graduate School of Medicine, Kyoto University
15:30
Neuron-glial interactions in health and disease: from cognition to cancer
Michelle Monje, MD, PhD
Stanford University
Howard Hughes Medical Institute
16:00
Delta One T cells: a new adoptive cell therapy for cancer
Bruno Silva-Santos, PhD
Faculdade de Medicina da Universidade de Lisboa
Instituto de Medicina Molecular (iMM)
16:30
Coffee Break
17:00
Networking
Meet the speaker
Meet the invited speakers in small groups and discuss your questions on research or career in 10 minute slots.
Social
CCU guided tours
Social
CCU guided tours
CCU guided tours
Explore the Champalimaud Centre for the Unknown in a guided tour to the building, including a visit to the labs and stories about the Champalimaud Research culture.
︎ Time in Lisbon (WEST)
9:00
Registration
9:30
Keynote Lecture
Keynote Lecture
Gerard Evan, PhD, FMedSci, FRS, FAACR
Department of Biochemistry, University of Cambridge
10:30
Dissecting and Rewiring Immune Cell Heterogeneity in Brain Tumors
Leila Akkari, PhD
Netherlands Cancer Institute (NKI)
Oncode Institute
11:00
Coffee Break
11:30
12:00
Jeffrey W. Pollard, PhD
College of Medicine and Veterinary Medicine, University of Edinburgh
12:30
Lunch
13:30
Poster Session I
15:30
Altered glycosylation in the tumor microenvironment: dissecting the molecular
mechanisms and understanding the clinical implications
Celso A. Reis, PhD
Institute for Research and Innovation in Health (i3s) & Institute of Molecular Pathology and Immunology of the University of Porto , ICBAS Institute of Biomedical Sciences Abel Salazar, Institute of Molecular Pathology and Immunology of the University of Porto
Institute for Research and Innovation in Health (i3s) & Institute of Molecular Pathology and Immunology of the University of Porto , ICBAS Institute of Biomedical Sciences Abel Salazar, Institute of Molecular Pathology and Immunology of the University of Porto
15:45
Physiological relevance of Flower during metastases development
Maria Bettencourt, PhD Candidate
Champalimaud Foundation
16:00
16:30
Coffee Break
17:00
Round-table
The Evolution of Mentorship in Space and Time: How to Tailor Your Mentorship
Round-table
Informal round-table session around finding and acting as a mentor throughout your working life, drawing on experiences from academics at different career stages.
The importance of adopting mentors throughout your career and bringing some kindness into the world
Neta Erez, Tel Aviv University
Train yourself as a mentor: schools outreach
Adriana Sánchez-Danés and Ciência di Noz Manera mentors:
The evolution of mentorship in space and time: how to tailor your mentorship
Ana Luisa Correia, Champalimaud Foundation
Sarah-Maria Fendt, VIB-KU
Sarah-Maria Fendt, VIB-KU
18:30
SocialDowntown Walk & Talk
Sunset drinks
Social
From CCU to Príncipe Real garden, join the Champalimaud Research community for a walk downtown and social drinks at Quiosque do Sr. Oliveira.
︎ Time in Lisbon (WEST)
9:00
Registration
9:30
Keynote Lecture
From bedside to bench: Critical unmet needs in Oncology
Fatima Cardoso, MD
Breast Unit, Champalimaud Foundation
ABC Global Alliance
10:30
Stromal and immune plasticity shape the metastatic microenvironment
Neta Erez, PhD
Sackler Faculty of Medicine, Tel Aviv University
11:00
Coffee Break
12:00
A vascular-restricted, tumor-induced neutrophil population drives vascular occlusion, pleomorphic necrosis, and metastasis
12:15
Bone Marrow Niche Dynamics and Metastatic Dormancy
Alexander Schäffer, PhD Candidate
Georg-Speyer-Haus - Institute for Tumor Biology and Experimental Therapy
12:30
Epigenetic regulation of fatty acid metabolism in metastasis: role of Schwann Cells
Salvador Aznar Benitah, PhD
Institute for Research in Biomedicine
13:00
Lunch
14:00
Poster Session II
16:00
Metabolic rewiring driving metastasis formation
Sarah-Maria Fendt, PhD
VIB-KU Leuven Centre for Cancer Biology
17:00
Coffee Break
17:30
Keynote Lecture
Keynote Lecture
Joan Massagué, PhD
MSKCC - Memorial Sloan Kettering Cancer Centre
18:30
Closing Remarks
19:00
SocialBoat tour
Social
20:00
SocialBanquet
Social
Poster Session I
Thu 20 Oct
13h30–15h30, Lisbon time1
Metastatic colorectal carcinoma-associated fibroblasts display an IGFBP2-dependent immunosuppressive effect on the tumour microenvironment
Cristiano Ramos, Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, et al.
2
Intra-Hospital Virtual Communities structure: impact on Patient Well-Being and in the Relationship with Physicians and Institutions
Ricardo Jorge Mendes da Silva, Faculty of Economics of University of Porto, Portuguese Institute of Oncology of Porto, et al.
3
Development and Characterization of Ovarian Cancer Zebrafish Avatars
Filipa Amorim, Champalimaud Foundation, et al.
4
Dendritic cells, bridging neuromodulation and immunity
Raquel Pessoa-Silva, Champalimaud Foundation, et al.
5
Study of immune-epithelial crosstalk using an innovated 3D culture system
Michelle Miniter, University of Cambridge, et al.
6
PLK4 potentiates anoikis-resistance of p53KO epithelial cells through P-cadherin upregulation in the tumor microenvironment
Irina Fonseca, Instituto Gulbenkian de Ciência (IGC) & Instituto de Investigação e Inovação em Saúde (i3S), Cancel Stem, Portuguese Consortium on Cancer Stem Cells, et al.
7
Dissecting intra-tumor clonal dynamics and its crosstalk with the microenvironment in a zebrafish xenograft model
Vanda Póvoa, Champalimaud Foundation, et al.
8
Novel players involved in Flower-mediated cell competition
Catarina Marçal-Costa, Champalimaud Foundation, et al.
9
Osteosarcoma-derived secretome modulate the lung microenvironment and accelerate lung metastasis formation
Sara F.F. Almeida, CIBIT/ICNAS - Institute for Nuclear Sciences Applied to Health, et al.
10
Impact of HER2+ brain-tropic breast cancer cells in blood-brain barrier permeability during the pre-metastatic niche formation
Liliana Santos, CIBIT/ICNAS – Institute for Nuclear Sciences Applied to Health, et al.
11
Deciphering the impact of cancer cell’ secretome and Its derived peptides on breast cancer brain metastasis
Rita de Carvalho, i3S – Instituto de Investigação e Inovação em Saúde, IPATIMUP – Instituto de Patologia e Imunologia Molecular, ICBAS- Instituto de Ciências Biomédicas Abel Salazar, et al.
12
Glycoprotein-A repetition predominant, a target of interest for SPECT imaging of triple negative breast cancer
Alexanne Bouchard, Centre George-François Leclerc, et al.
13
Low doses of ionizing radiation modulate the pre‐metastatic niche and induce metastasis development.
Paula Oliveira, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, et al.
14
Evolution of the mutational landscape of human healthy and precancerous oral epithelium – a role for NOTCH1
Inês Ferreira, University of Cambridge, et al.
15
RIPK3 in the interface of immunogenic cell death and microenvironment in hepatocellular carcinoma
André Cardador, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon, et al.
16
Premalignant cells: should I stay (and expand) or should I go (and survive)?
Catarina Brás-Pereira, Champalimaud Foundation, et al.
17
Human bladder physiological 3D culture
Jose A Valverde-Lopez, University of Cambridge, et al.
18
Impact of LAMA2-deficiency in cancer
Ana Sofia Lopes, cE3c-CHANGE, Faculdade de Ciências da Universidade de Lisboa and Centro Hospitalar de Lisboa Ocidental (CHLO), et al.
19
Characterization of cell competition between cancer cells and hepatocytes
Andrea Spinazzola, Champalimaud Foundation, et al.
20
Vα7.2 + Mucosal-associated invariant T cells from PDAC recognize autologous tumor cells
Jéssica Oliveira Kamiki, Champalimaud Foundation, et al.
21
Molecular phenotyping of Prostate Cancer microenvironment, with emphasis in fibroblast activation and macrophage polarization
Inês Pontinha, Champalimaud Foundation, et al.
22
Are you talking to me? How multiple myeloma-derived extracellular vesicles reprogramme the bone marrow immune niche
Raquel Lopes, Champalimaud Foundation and Faculty of Medicine of Lisbon, et al.
23
Identification of new key players of cell competition in a colon cancer model
Ana C. Queirós, Champalimaud Foundation, et al.
24
Uncovering the similarities and differences between paediatric and adult melanoma
Sofia Carvalho-Marques, Champalimaud Foundation, et al.
25
Ikebana, a novel player in Cell Competition
Mariana Reis, Champalimaud Foundation, et al.
26
Role of Azot upon Damage.
Andrés Gutiérrez, Champalimaud Foundation, et al.
27
PTMA interacts with Flower “Win” isoform promoting cancer growth and invasion
Denise Camacho, Champalimaud Foundation, et al.
28
The Molecular and Transgenic Tools Platform at Champalimaud Foundation
Ana Raquel Tomás, Champalimaud Foundation, et al.
29
Ovarian cancer Zebrafish Avatars for personalized multiple drug testing
Marta F. Estrada, Champalimaud Foundation , et al.
Poster Session II
Fri 21 Oct
14h - 16h, Lisbon time30
Precision nanomedicine-based immunotherapy to overcome immunosuppression against metastatic melanoma
Bárbara Carreira, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon, et al.
31
Innate neuroimmune interactions in pancreatic cancer
Sara T. Correia, LiMM Therapeutics and Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal, et al.
32
X-ray and spectroscopic investigation of the prostate cancer tissue environment
Sarah Gosling, School of Chemical and Physical Sciences, Keele University, et al.
33
Fishing for new immunotherapy compounds to boost innate-tumor rejection
Ana B. Machado, Champalimaud Foundation, et al.
34
The prognostic value of the Sialyl-Tn biomarker in triple negative breast cancer
Rita Adubeiro Lourenço, UCIBIO, Departamento Ciências da Vida, NOVA School of Science and Technology, NOVA University of Lisbon, Associate Laboratory i4HB - Institute for Health and Bioeconomy, School of Science and Technology, NOVA University, et al.
35
Development of Glioblastoma zebrafish xenograft model
Márcia Fontes, Champalimaud Foundation, et al.
36
The influence of tumor microenvironment on the effects induced by cannabidiol when combined with exemestane in estrogen receptor-positive breast tumors
Cristina Ferreira Almeida, UCIBIO.REQUIMTE, Faculty of Farmacy, University of Porto, et al.
37
Zebrafish Avatar model towards personalised Breast Cancer therapy
Raquel Mendes, Champalimaud Foundation, et al.
38
The role of aberrant glycosylation in gastric cancer extracellular vesicles
José Pires, i3s, IPATIMUP, Faculty of Medicine of the University of Porto, et al.
39
The role of extracellular vesicles carrying cancer-associated glycans in intercellular communication
Daniela Freitas, i3S-Institute for Research and Innovation in Health, University of Porto & IPATIMUP -Institute of Molecular Pathology and Immunology, University of Porto & Departments of Pediatrics, Weill Cornell Medicine, et al.
40
Cancer Research and the Champalimaud Fish Platform
Joana Monteiro, Champalimaud Foundation, et al.
41
Unleashing natural killer (NK) cells to promote anti-tumour immunity
Ioanna Tsoukala, Georg-Speyer-Haus- Institute for Tumor Biology and Experimental Therapy, et al.
42
Lactate and immune-editing in TIL from patients with GI cancer
Frederico Mateus, Champalimaud Foundation, et al.
43
TIL expansion and T-cell function edited by pH
Bernardo Marinheiro, Champalimaud Foundation, et al.
44
TCRcloud: a screening tool for biologically and clinically relevant TCR repertoire landscapes
Eric de Sousa, Champalimaud Foundation, et al.
45
Tumor – reactive γδ+ TILs from patients with epithelial cancer
Joana R. Lérias, Champalimaud Foundation, et al.
47
Human tumor-infiltrating lymphocyte reactivity against pancreatic cancer epitopes is modulated by interleukin 12
Carolina M. Gorgulho, Champalimaud Foundation, et al.
48
Tumor Infiltrating Lymphocytes are activated by Shingosine-1-phosphate
Patrícia Alexandra António, Champalimaud Foundation, et al.
49
Location of Tumor Infiltrating Lymphocytes within the Tumor Microenvironment is associated with ‘young’ and tumor-reactive TIL populations
Rodrigo Eduardo, Champalimaud Foundation, et al.
50
Establishment of a Personalized 3D Ex Vivo Model for Multiple Myeloma
Diana Lourenço, Champalimaud Foundation, et al.
51
Compound Screening in a 3D Spheroid Model Identifies Curcumin Analog as a Colorectal Cancer Stem Cell Inhibitor
Vanda Marques, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon , et al.
52
Charaterisation of the colon adenocarcinoma microenvironment with a focus on natural killer cells
Hasti Calá, Champalimaud Foundation, et al.
Champalimaud Foundation
Av. Brasília
1400-038 Lisboa - Portugal
Av. Brasília
1400-038 Lisboa - Portugal