Poster Session I

Thu 20 Oct

13h30–15h30, Lisbon time

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1

Metastatic colorectal carcinoma-associated fibroblasts display an IGFBP2-dependent immunosuppressive effect on the tumour microenvironment

Cristiano Ramos, Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, et al.

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2

Intra-Hospital Virtual Communities structure: impact on Patient Well-Being and in the Relationship with Physicians and Institutions

Ricardo Jorge Mendes da Silva, Faculty of Economics of University of Porto, Portuguese Institute of Oncology of Porto, et al.

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3

Development and Characterization of Ovarian Cancer Zebrafish Avatars

Filipa Amorim, Champalimaud Foundation, et al.

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4

Dendritic cells, bridging neuromodulation and immunity

Raquel Pessoa-Silva, Champalimaud Foundation, et al.

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5

Study of immune-epithelial crosstalk using an innovated 3D culture system

Michelle Miniter, University of Cambridge, et al.

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6

PLK4 potentiates anoikis-resistance of p53KO epithelial cells through P-cadherin upregulation in the tumor microenvironment

Irina Fonseca, Instituto Gulbenkian de Ciência (IGC) & Instituto de Investigação e Inovação em Saúde (i3S), Cancel Stem, Portuguese Consortium on Cancer Stem Cells, et al.

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7

Dissecting intra-tumor clonal dynamics and its crosstalk with the microenvironment in a zebrafish xenograft model

Vanda Póvoa, Champalimaud Foundation, et al.

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8

Novel players involved in Flower-mediated cell competition

Catarina Marçal-Costa, Champalimaud Foundation, et al.

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9

Osteosarcoma-derived secretome modulate the lung microenvironment and accelerate lung metastasis formation

Sara F.F. Almeida, CIBIT/ICNAS - Institute for Nuclear Sciences Applied to Health, et al.

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10

Impact of HER2+ brain-tropic breast cancer cells in blood-brain barrier permeability during the pre-metastatic niche formation

Liliana Santos, CIBIT/ICNAS – Institute for Nuclear Sciences Applied to Health, et al.

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11

Deciphering the impact of cancer cell’ secretome and Its derived peptides on breast cancer brain metastasis

Rita de Carvalho, i3S – Instituto de Investigação e Inovação em Saúde, IPATIMUP – Instituto de Patologia e Imunologia Molecular, ICBAS- Instituto de Ciências Biomédicas Abel Salazar, et al.

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12

Glycoprotein-A repetition predominant, a target of interest for SPECT imaging of triple negative breast cancer

Alexanne Bouchard, Centre George-François Leclerc, et al.

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13

Low doses of ionizing radiation modulate the pre‐metastatic niche and induce metastasis development.

Paula Oliveira, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, et al.

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14

Evolution of the mutational landscape of human healthy and precancerous oral epithelium – a role for NOTCH1

Inês Ferreira, University of Cambridge, et al.

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15

RIPK3 in the interface of immunogenic cell death and microenvironment in hepatocellular carcinoma

André Cardador, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon, et al.

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16

Premalignant cells: should I stay (and expand) or should I go (and survive)?

Catarina Brás-Pereira, Champalimaud Foundation, et al.

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17

Human bladder epithelioids

Jose A Valverde-Lopez, University of Cambridge, et al.

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18

Impact of LAMA2-deficiency in cancer

Ana Sofia Lopes, cE3c-CHANGE, Faculdade de Ciências da Universidade de Lisboa and Centro Hospitalar de Lisboa Ocidental (CHLO), et al.

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19

Characterization of cell competition between cancer cells and hepatocytes

Andrea Spinazzola, Champalimaud Foundation, et al.

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20

Vα7.2 + Mucosal-associated invariant T cells from PDAC recognize autologous tumor cells

Jéssica Oliveira Kamiki, Champalimaud Foundation, et al.

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21

Molecular phenotyping of Prostate Cancer microenvironment, with emphasis in fibroblast activation and macrophage polarization

Inês Pontinha, Champalimaud Foundation, et al.

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22

Are you talking to me? How multiple myeloma-derived extracellular vesicles reprogramme the bone marrow immune niche

Raquel Lopes, Champalimaud Foundation and Faculty of Medicine of Lisbon, et al.

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23

Identification of new key players of cell competition in a colon cancer model

Ana C. Queirós, Champalimaud Foundation, et al.

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24

Uncovering the similarities and differences between paediatric and adult melanoma

Sofia Carvalho-Marques, Champalimaud Foundation, et al.

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25

Ikebana, a novel player in Cell Competition

Mariana Reis, Champalimaud Foundation, et al.

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26

Role of Azot upon Damage.

Andrés Gutiérrez, Champalimaud Foundation, et al.

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27

PTMA interacts with Flower “Win” isoform promoting cancer growth and invasion

Denise Camacho, Champalimaud Foundation, et al.

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28

The Molecular and Transgenic Tools Platform at Champalimaud Foundation

Ana Raquel Tomás, Champalimaud Foundation, et al.

Poster Session II
Fri 21 Oct

14h - 16h, Lisbon time

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29

Evaluation of molecular changes in patients with coloretal cancer (CRC) and applicability in the liquid biopsy technique

Bianca Gomes Fernandes, Centro de Tecnologia em Medicina Molecular, Faculdade de Medicina, Universidade Federal de Minas Gerais, et al.

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30

Precision nanomedicine-based immunotherapy to overcome immunosuppression against metastatic melanoma

Bárbara Carreira, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon, et al.

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31

Innate neuroimmune interactions in pancreatic cancer

Sara T. Correia, LiMM Therapeutics and Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal, et al.

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32

X-ray and spectroscopic investigation of the prostate cancer tissue environment

Sarah Gosling, School of Chemical and Physical Sciences, Keele University, et al.

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33

Fishing for new immunotherapy compounds to boost innate-tumor rejection

Ana B. Machado, Champalimaud Foundation, et al.

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34

The prognostic value of the Sialyl-Tn biomarker in triple negative breast cancer

Rita Adubeiro Lourenço, UCIBIO, Departamento Ciências da Vida, NOVA School of Science and Technology, NOVA University of Lisbon, Associate Laboratory i4HB - Institute for Health and Bioeconomy, School of Science and Technology, NOVA University, et al.

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35

Development of Glioblastoma zebrafish xenograft model

Márcia Fontes, Champalimaud Foundation, et al.

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36

The influence of tumor microenvironment on the effects induced by cannabidiol when combined with exemestane in estrogen receptor-positive breast tumors

Cristina Ferreira Almeida, UCIBIO.REQUIMTE, Faculty of Farmacy, University of Porto, et al.

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37

Zebrafish Avatar model towards personalised Breast Cancer therapy

Raquel Mendes, Champalimaud Foundation, et al.

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38

The role of aberrant glycosylation in gastric cancer extracellular vesicles

José Pires, i3s, IPATIMUP, Faculty of Medicine of the University of Porto, et al.

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39

The role of extracellular vesicles carrying cancer-associated glycans in intercellular communication

Daniela Freitas, i3S-Institute for Research and Innovation in Health, University of Porto & IPATIMUP -Institute of Molecular Pathology and Immunology, University of Porto & Departments of Pediatrics, Weill Cornell Medicine, et al.

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40

Cancer Research and the Champalimaud Fish Platform

Joana Monteiro, Champalimaud Foundation, et al.

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41

Unleashing natural killer (NK) cells to promote anti-tumour immunity

Ioanna Tsoukala, Georg-Speyer-Haus- Institute for Tumor Biology and Experimental Therapy, et al.

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42

Lactate and immune-editing in TIL from patients with GI cancer

Frederico Mateus, Champalimaud Foundation, et al.

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43

TIL expansion and T-cell function edited by pH

Bernardo Marinheiro, Champalimaud Foundation, et al.

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44

TCRcloud: a screening tool for biologically and clinically relevant TCR repertoire landscapes 

Eric de Sousa, Champalimaud Foundation, et al.

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45

Tumor – reactive γδ+ TILs from patients with epithelial cancer

Joana R. Lérias, Champalimaud Foundation, et al.

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46

Ovarian cancer Zebrafish Avatars for personalized multiple drug testing

Marta F. Estrada, Champalimaud Foundation , et al.

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47

Human tumor-infiltrating lymphocyte reactivity against pancreatic cancer epitopes is modulated by interleukin 12

Carolina M. Gorgulho, Champalimaud Foundation, et al.

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48

Tumor Infiltrating Lymphocytes are activated by Shingosine-1-phosphate

Patrícia Alexandra António, Champalimaud Foundation, et al.

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49

Location of Tumor Infiltrating Lymphocytes within the Tumor Microenvironment is associated with ‘young’ and tumor-reactive TIL populations

Rodrigo Eduardo, Champalimaud Foundation, et al.

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50

Establishment of a Personalized 3D Ex Vivo Model for Multiple Myeloma

Diana Lourenço, Champalimaud Foundation, et al.

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51

Compound Screening in a 3D Spheroid Model Identifies Curcumin Analog as a Colorectal Cancer Stem Cell Inhibitor

Vanda Marques, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon , et al.

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52

Charaterisation of the colon adenocarcinoma microenvironment with a focus on natural killer cells

Hasti Calá, Champalimaud Foundation, et al.