Poster Session I

Thu 20 Oct

13h30–15h30, Lisbon time

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1

Metastatic colorectal carcinoma-associated fibroblasts display an IGFBP2-dependent immunosuppressive effect on the tumour microenvironment

Cristiano Ramos, Department of General Surgery, Division of Visceral Surgery, Medical University of Vienna, et al.

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2

Intra-Hospital Virtual Communities structure: impact on Patient Well-Being and in the Relationship with Physicians and Institutions

Ricardo Jorge Mendes da Silva, Faculty of Economics of University of Porto, Portuguese Institute of Oncology of Porto, et al.

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3

Development and Characterization of Ovarian Cancer Zebrafish Avatars

Filipa Amorim, Champalimaud Foundation, et al.

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4

Dendritic cells, bridging neuromodulation and immunity

Raquel Pessoa-Silva, Champalimaud Foundation, et al.

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5

Study of immune-epithelial crosstalk using an innovated 3D culture system

Michelle Miniter, University of Cambridge, et al.

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6

PLK4 potentiates anoikis-resistance of p53KO epithelial cells through P-cadherin upregulation in the tumor microenvironment

Irina Fonseca, Instituto Gulbenkian de Ciência (IGC) & Instituto de Investigação e Inovação em Saúde (i3S), Cancel Stem, Portuguese Consortium on Cancer Stem Cells, et al.

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7

Dissecting intra-tumor clonal dynamics and its crosstalk with the microenvironment in a zebrafish xenograft model

Vanda Póvoa, Champalimaud Foundation, et al.

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8

Novel players involved in Flower-mediated cell competition

Catarina Marçal-Costa, Champalimaud Foundation, et al.

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9

Osteosarcoma-derived secretome modulate the lung microenvironment and accelerate lung metastasis formation

Sara F.F. Almeida, CIBIT/ICNAS - Institute for Nuclear Sciences Applied to Health, et al.

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10

Impact of HER2+ brain-tropic breast cancer cells in blood-brain barrier permeability during the pre-metastatic niche formation

Liliana Santos, CIBIT/ICNAS – Institute for Nuclear Sciences Applied to Health, et al.

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11

Deciphering the impact of cancer cell’ secretome and Its derived peptides on breast cancer brain metastasis

Rita de Carvalho, i3S – Instituto de Investigação e Inovação em Saúde, IPATIMUP – Instituto de Patologia e Imunologia Molecular, ICBAS- Instituto de Ciências Biomédicas Abel Salazar, et al.

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12

Glycoprotein-A repetition predominant, a target of interest for SPECT imaging of triple negative breast cancer

Alexanne Bouchard, Centre George-François Leclerc, et al.

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13

Low doses of ionizing radiation modulate the pre‐metastatic niche and induce metastasis development.

Paula Oliveira, Centro Cardiovascular da Universidade de Lisboa (CCUL@RISE), Faculdade de Medicina, Universidade de Lisboa, et al.

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14

Evolution of the mutational landscape of human healthy and precancerous oral epithelium – a role for NOTCH1

Inês Ferreira, University of Cambridge, et al.

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15

RIPK3 in the interface of immunogenic cell death and microenvironment in hepatocellular carcinoma

André Cardador, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon, et al.

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16

Premalignant cells: should I stay (and expand) or should I go (and survive)?

Catarina Brás-Pereira, Champalimaud Foundation, et al.

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17

Human bladder physiological 3D culture

Jose A Valverde-Lopez, University of Cambridge, et al.

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18

Impact of LAMA2-deficiency in cancer

Ana Sofia Lopes, cE3c-CHANGE, Faculdade de Ciências da Universidade de Lisboa and Centro Hospitalar de Lisboa Ocidental (CHLO), et al.

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19

Characterization of cell competition between cancer cells and hepatocytes

Andrea Spinazzola, Champalimaud Foundation, et al.

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20

Vα7.2 + Mucosal-associated invariant T cells from PDAC recognize autologous tumor cells

Jéssica Oliveira Kamiki, Champalimaud Foundation, et al.

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21

Molecular phenotyping of Prostate Cancer microenvironment, with emphasis in fibroblast activation and macrophage polarization

Inês Pontinha, Champalimaud Foundation, et al.

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22

Are you talking to me? How multiple myeloma-derived extracellular vesicles reprogramme the bone marrow immune niche

Raquel Lopes, Champalimaud Foundation and Faculty of Medicine of Lisbon, et al.

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23

Identification of new key players of cell competition in a colon cancer model

Ana C. Queirós, Champalimaud Foundation, et al.

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24

Uncovering the similarities and differences between paediatric and adult melanoma

Sofia Carvalho-Marques, Champalimaud Foundation, et al.

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25

Ikebana, a novel player in Cell Competition

Mariana Reis, Champalimaud Foundation, et al.

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26

Role of Azot upon Damage.

Andrés Gutiérrez, Champalimaud Foundation, et al.

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27

PTMA interacts with Flower “Win” isoform promoting cancer growth and invasion

Denise Camacho, Champalimaud Foundation, et al.

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28

The Molecular and Transgenic Tools Platform at Champalimaud Foundation

Ana Raquel Tomás, Champalimaud Foundation, et al.

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29

Ovarian cancer Zebrafish Avatars for personalized multiple drug testing

Marta F. Estrada, Champalimaud Foundation , et al.

Poster Session II
Fri 21 Oct

14h - 16h, Lisbon time

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30

Precision nanomedicine-based immunotherapy to overcome immunosuppression against metastatic melanoma

Bárbara Carreira, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon, et al.

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31

Innate neuroimmune interactions in pancreatic cancer

Sara T. Correia, LiMM Therapeutics and Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal, et al.

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32

X-ray and spectroscopic investigation of the prostate cancer tissue environment

Sarah Gosling, School of Chemical and Physical Sciences, Keele University, et al.

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33

Fishing for new immunotherapy compounds to boost innate-tumor rejection

Ana B. Machado, Champalimaud Foundation, et al.

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34

The prognostic value of the Sialyl-Tn biomarker in triple negative breast cancer

Rita Adubeiro Lourenço, UCIBIO, Departamento Ciências da Vida, NOVA School of Science and Technology, NOVA University of Lisbon, Associate Laboratory i4HB - Institute for Health and Bioeconomy, School of Science and Technology, NOVA University, et al.

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35

Development of Glioblastoma zebrafish xenograft model

Márcia Fontes, Champalimaud Foundation, et al.

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36

The influence of tumor microenvironment on the effects induced by cannabidiol when combined with exemestane in estrogen receptor-positive breast tumors

Cristina Ferreira Almeida, UCIBIO.REQUIMTE, Faculty of Farmacy, University of Porto, et al.

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37

Zebrafish Avatar model towards personalised Breast Cancer therapy

Raquel Mendes, Champalimaud Foundation, et al.

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38

The role of aberrant glycosylation in gastric cancer extracellular vesicles

José Pires, i3s, IPATIMUP, Faculty of Medicine of the University of Porto, et al.

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39

The role of extracellular vesicles carrying cancer-associated glycans in intercellular communication

Daniela Freitas, i3S-Institute for Research and Innovation in Health, University of Porto & IPATIMUP -Institute of Molecular Pathology and Immunology, University of Porto & Departments of Pediatrics, Weill Cornell Medicine, et al.

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40

Cancer Research and the Champalimaud Fish Platform

Joana Monteiro, Champalimaud Foundation, et al.

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41

Unleashing natural killer (NK) cells to promote anti-tumour immunity

Ioanna Tsoukala, Georg-Speyer-Haus- Institute for Tumor Biology and Experimental Therapy, et al.

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42

Lactate and immune-editing in TIL from patients with GI cancer

Frederico Mateus, Champalimaud Foundation, et al.

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43

TIL expansion and T-cell function edited by pH

Bernardo Marinheiro, Champalimaud Foundation, et al.

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44

TCRcloud: a screening tool for biologically and clinically relevant TCR repertoire landscapes 

Eric de Sousa, Champalimaud Foundation, et al.

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45

Tumor – reactive γδ+ TILs from patients with epithelial cancer

Joana R. Lérias, Champalimaud Foundation, et al.

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47

Human tumor-infiltrating lymphocyte reactivity against pancreatic cancer epitopes is modulated by interleukin 12

Carolina M. Gorgulho, Champalimaud Foundation, et al.

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48

Tumor Infiltrating Lymphocytes are activated by Shingosine-1-phosphate

Patrícia Alexandra António, Champalimaud Foundation, et al.

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49

Location of Tumor Infiltrating Lymphocytes within the Tumor Microenvironment is associated with ‘young’ and tumor-reactive TIL populations

Rodrigo Eduardo, Champalimaud Foundation, et al.

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50

Establishment of a Personalized 3D Ex Vivo Model for Multiple Myeloma

Diana Lourenço, Champalimaud Foundation, et al.

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51

Compound Screening in a 3D Spheroid Model Identifies Curcumin Analog as a Colorectal Cancer Stem Cell Inhibitor

Vanda Marques, Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon , et al.

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52

Charaterisation of the colon adenocarcinoma microenvironment with a focus on natural killer cells

Hasti Calá, Champalimaud Foundation, et al.