__ Check the detailed programme __ 4 keynote, 16 invited, and 7 selected speakers + 3 invited editors confirmed __ This event already happened __ Champalimaud Research Symposium 




︎  Time in Lisbon (WEST)

Posters I



thu 17 — 13:30–15h30

1

Exploring Novel LOXL2 Inhibitors: Implications for Breast Cancer Treatment


Sandra Ferreira, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies and Universidad de Alcalá de Henares; Daniel J. V. A. dos Santos, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies; Ana M. Díaz-Lanza, CBIOS, Universidad de Alcalá de Henares; João G. Costa, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies; Nuno Saraiva, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies; Patrícia Rijo, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies; Ana S. Fernandes, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies



2

Characterizing the stromal-immune crosstalk in pancreatic cancer


Sara Trindade Correia[1,2], Lynn Vermeer[1], Maria Keridon[1], Klaas van Gisbergen[1], and Inês Ramos[1]; 1- Cancer and Physiology department, Champalimaud Research, Champalimaud Centre for the Unknown, Lisboa, Portugal  2- Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal



3

Macrophages drive the earliest anti-tumoral response to BCG therapy by directly killing bladder cancer through TNF signalling

Mayra Martinez-Lopez, Universidad de las Américas; Cátia Rebelo de Almeida, Champalimaud Foundation; Marcia Fontes, Champalimaud Foundation; Raquel Valente Mendes, Champalimaud Foundation; Stefan H.E. Kaufmann, Max Planck Institute for Infection Biology; Rita Fior, Champalimaud Foundation



4

Fishing for New Immunotherapy Compounds to Boost Innate-Tumour Rejection


Ana Beatriz Machado, Champalimaud Foundation; Inês Oliveira, Champalimaud Foundation; Luís Leite, Champalimaud Foundation; Domenico Calaffato, Champalimaud Foundation; Cátia Rebelo Almeida, Champalimaud Foundation; Bruna Costa, Champalimaud Foundation; Vanda Póvoa, Champalimaud Foundation; Rita Fior, Champalimaud Foundation



5

Understanding Metastasis Organotropism Patterns Through Within-cell and Between-cells Molecular Interaction Networks


João A. I. Miranda, BioISI — BioSystems and Integrative Sciences Institute, Faculdade de Ciências, Universidade de Lisboa; Margarida Carrolo, Hematology and Oncology Department, CUF Oncologia; António Quintela, Hematology and Oncology Department, CUF Oncologia; Francisco R. Pinto, BioISI — BioSystems and Integrative Sciences Institute, Faculdade de Ciências, Universidade de Lisboa



6

zAvatar-test forecasts patient's treatment outcome in colorectal cancer


Bruna Costa, Champalimaud Foundation; Marta F. Estrada, Champalimaud Foundation; António Gomes, Surgery Unit, Hospital Prof. Doutor Fernando Fonseca; Laura Fernandez, Colorectal Surgery Department, Champalimaud Clinical Centre; José M.Azevedo, Colorectal Surgery Department, Champalimaud Clinical Centre; Vanda Póvoa, Champalimaud Foundation; Márcia Fontes, Champalimaud Foundation; António Alves, Institute of Pathological Anatomy, Faculty of Medicine of the University of Lisbon; António Galzerano, Pathology Service, Champalimaud Clinical Centre; Mireia Castillo-Martin, Pathology Service, Champalimaud Clinical Centre; Ignacio Herrando, Colorectal Surgery Department, Champalimaud Clinical Centre; Shermann Brandão, Digestive Unit, Champalimaud Clinical Centre; Vítor Nunes, Surgery Unit, Hospital Prof. Doutor Fernando Fonseca; Carlos Carvalho, Digestive Unit, Champalimaud Clinical Centre; Amjad Parvaiz, Colorectal Surgery Department, Champalimaud Clinical Centre; Ana Marreiros, Faculty of Medicine and Biomedical Sciences, University of Algarve; Rita Fior, Champalimaud Foundation



7

The Molecular and Transgenic Tools Platform at Champalimaud Foundation


Ana João Martins, Champalimaud Foundation; Ana Raquel Tomás, Champalimaud Foundation; Catarina Miranda, Champalimaud Foundation; Hugo Lopes, Champalimaud Foundation; Marta Barbosa, Champalimaud Foundation; Renato Xavier, Champalimaud Foundation; Ana Catarina Certal, Champalimaud Foundation



8

Development of tissue resident memory T cells in pancreatic cancer


Hester Heimans, Leiden University Medical Center; Tsolere Arakelian, Leiden University Medical Center; Lisa Griffioen, Leiden University Medical Center; Marjolein Sluijter, Leiden University Medical Center; Gaby Schaap, Leiden University Medical Center; Natasja Kragten, University of Amsterdam; Lynn Vermeer, Champalimaud Foundation; Maria Keridon, Champalimaud Foundation; Sjoerd H. van der Burg, Leiden University Medical Center; Klaas van Gisbergen, Champalimaud Foundation and University of Amsterdam; Thorbald van Hall, Leiden University Medical Center



9

Deciphering Tissue-Resident Memory T Cells Differentiation Pathway in Breast Cancer


Daniela Amaral-Silva, Champalimaud Foundation; Raquel L. Sequeira, Champalimaud Foundation; Klaas van Gisbergen, Champalimaud Foundation



10

A neuroepithelial circuit responsible for intestinal immunity and physiology


Roksana M. Pirzgalska, Champalimaud Foundation; Beatriz Henriques Alves, Champalimaud Foundation; Madalena Pereira, Champalimaud Foundation; Bruno Raposo, Champalimaud Foundation; Hélder Ribeiro, Champalimaud Foundation; Henrique Veiga-Fernandes, Champalimaud Foundation



11

Size-exclusion Chromatography: a Path to Higher Yield and Reproducibility Compared to Sucrose Cushion Ultracentrifugation for Extracellular Vesicles Isolation in Multiple Myeloma


Madalena Grenhas, Champalimaud Foundation; Raquel Lopes, Champalimaud Foundation and Faculty of Medicine, University of Lisbon; Bruna Velosa Ferreira, Champalimaud Foundation, Filipa Barahona, Champalimaud Foundation and Faculty of Medical Sciences, NOVA Medical School; Cristina João, Champalimaud Foundation, Faculty of Medicine, University of Lisbon and Faculty of Medical Sciences, NOVA Medical School; Emilie Arnault Carneiro, Champalimaud Foundation



12

The TMBIM4 Golgi Ion Channel Shapes Cancer Cell Survival by Controlling GSH Availability


Marta Martins, CBIOS, Universidade Lusófona Research Center for Biosciences & Health and Universidad de Alcalá de Henares; Nuno Almeida, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies; Marisa Nicolai, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies; Giorgia Del Favero, University of Vienna; Ana S. Fernandes, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies; Nuno Saraiva, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies



13

A glia-derived cytokine regulates proliferation in brain tissue


Anabel R. Simões, Champalimaud Foundation; Carolina Alves, Champalimaud Foundation; Christa Rhiner, Champalimaud Foundation



14

Targeting RUNX transcriptional activity enhances drug sensitivity and reduces aggressiveness in triple-negative breast cancer


Sofía María Sosa, Universidad de Buenos Aires (UBA); Natalia Brenda Fernández, iB3-FBMC-FCEN-UBA and CONICET; Facundo Luis Couto, iB3-FBMC-FCEN-UBA;
Natalia Rubinstein, iB3-FBMC-FCEN-UBA and CONICET




15

Deciphering the role of tissue innervation in metastatic breast cancer dormancy


Andreia M. Gonçalves, Champalimaud Foundation and ITQB Universidade NOVA de Lisboa; Ana Luísa Correia, Champalimaud Foundation



16

Calcium-ROS-mediated Injury Sensing Promotes Proliferation in the Adult Brain of Drosophila


Carolina Alves, Champalimaud Foundation; Anabel Simões, Champalimaud Foundation; Christa Rhiner, Champalimaud Foundation



17

Development and Characterization of Ovarian Cancer zAvatars


Filipa Amorim, Champalimaud Foundation; Marta F Estrada, Champalimaud Foundation; Cátia Rebelo de Almeida, Champalimaud Foundation; Márcia Fontes, Champalimaud Foundation; João Casanova, Champalimaud Clinical Centre; Rita Marques, Champalimaud Clinical Centre; Maria de Lurdes Batarda, Champalimaud Clinical Centre; Filipa Silva, Champalimaud Clinical Centre; Sónia Ferreira, Champalimaud Clinical Centre; Henrique Nabais; Champalimaud Clinical Centre; Rita Fior, Champalimaud Foundation



18

Unravelling Circadian NeuroEndocrine-Immune Axis in Health and Disease


Cristina Godinho-Silva, Champalimaud Foundation; Miguel Rendas, Champalimaud Foundation; Bruno Raposo, Champalimaud Foundation; Rita G. Domingues, University of Manchester; Hélder Ribeiro, Champalimaud Foundation; Henrique Veiga-Fernandes, Champalimaud Foundation



19

Dynamic remodelling of the tissue microenvironment promotes proliferation in the context of nervous tissue injury and tumour formation


Juan Sánchez, Champalimaud Foundation; Mariana Santos, Champalimaud Foundation; Anabel Simões, Champalimaud Foundation; Carolina Alves, Champalimaud Foundation; Sergio Casas-Tintó, Instituto de Salud Carlos III; Christa Rhiner, Champalimaud Foundation



20

Ovarian cancer Zebrafish Avatars for personalised multiple drug testing


Marta F Estrada, Champalimaud Foundation; Filipa Amorim, Champalimaud Foundation; Cátia Rebelo de Almeida, Champalimaud Foundation; Márcia Fontes, Champalimaud Foundation; João Casanova, Champalimaud Clinical Centre; Rita Canas-Marques, Champalimaud Clinical Centre; Mireia Castillo Martin, Champalimaud Clinical Centre; Maria de Lurdes Batarda, Champalimaud Clinical Centre; Filipa Silva, Champalimaud Clinical Centre; Sónia Ferreira, Champalimaud Clinical Centre; Henrique Nabais, Champalimaud Clinical Centre, l; Rita Fior, Champalimaud Foundation



21

Zebrafish Avatar-test predicts Patient’s Tumor Response to Chemotherapy in Breast Cancer: a Co-clinical Study towards Personalized Medicine


Raquel V. Mendes, Champalimaud Foundation; Joana M. Ribeiro, Gustave Roussy, Département de Médecine Oncologique; Helena Gouveia, Champalimaud Clinical Centre,; Cátia Rebelo de Almeida, Champalimaud Foundation; Mireia Castillo-Martin,Champalimaud Foundation and Champalimaud Clinical Centre; Maria José Brito, Champalimaud Clinical Centre; Rita Canas-Marques, Champalimaud Clinical Centre; Eva Batista, Champalimaud Clinical Centre; Celeste Alves, Champalimaud Clinical Center; Berta Sousa, Champalimaud Clinical Center; Pedro Gouveia, Champalimaud Clinical Centre; Miguel Godinho Ferreira, Université Côte d’Azur; Maria João Cardoso, Champalimaud Clinical Centre, and Faculdade de Medicina, Universidade de Lisboa; Fatima Cardoso, Champalimaud Clinical Centre,; Rita Fior, Champalimaud Foundation



22

Are Children Just Little Adults? Tackling the Role of the Tumour Microenvironment in Pediatric and Adult Melanoma Progression and Therapy Response


Sofia Carvalho-Marques, Champalimaud Foundation; Raquel Soares, Champalimaud Foundation; Sara Canato, Champalimaud Foundation; María Martínez-Lopez, Champalimaud Foundation; Alizée Vercauteren Drubbel, Université Libre de Bruxelles; Tânia Carvalho, Champalimaud Foundation; Benjamin Beck, Université Libre de Bruxelles; Henrique Veiga-Fernandes, Champalimaud Foundation; Adriana Sánchez-Danés, Champalimaud Foundation



23

Tracing the Impact of Neural Stem Cell Re-activation in Response to Tissue Stress


Margarida Caio, Champalimaud Foundation; Christa Rhiner, Champalimaud Foundation



24

Unveiling Innate Immune Evasion in a Zebrafish Xenograft Model


Vanda Povoa, Champalimaud Foundation; Cátia Rebelo de Almeida, Champalimaud Foundation; Mariana Maia-Gil, Champalimaud Foundation; Daniel Sobral, FCT-NOVA; Micaela Domingues, Champalimaud Foundation; Mayra Martinez, Champalimaud Foundation; Miguel de Almeida Fuzeta, Champalimaud Foundation; Carlos Silva, Champalimaud Foundation; Ana Rita Grosso, FCT-NOVA; Rita Fior, Champalimaud Foundation



25

Polyphenol Metabolites: mechanistic insights towards nutritional strategies to prevent renal cancer development


Íris Guerreiro, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies and Universidad de Alcalá de Henares; Diogo Carregosa, NOVA Medical School; Nuno Saraiva, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies; Nuno G. Oliveira, Universidade de Lisboa; João G. Costa, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies; Cláudia Nunes dos Santos, NOVA Medical School; Ana S. Fernandes, CBIOS, Universidade Lusófona Research Center for Biosciences & Health Technologies