posters I
wednesday 14
14:00 – 15h30
14:00 – 15h30
1
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2
Fishing for New Immunotherapy Compounds to Boost Innate-Tumor Rejection
Ana Beatriz Machado 1, Inês Oliveira 1, Carlos Labão-Almeida 2,3, Vanda Póvoa 1, Luís Leite 1, Domenico Calaffato 1, Beatriz Sebo 1, Cátia Rebelo de Almeida 1, Bruna Costa 1, Renata Couto 2,3, Gonçalo Bernardes 2,3,4, and Rita Fior 1
1. Champalimaud Foundation, Lisbon, Portugal
2. Gulbenkian Institute of Molecular Medicine, Lisbon, Portugal
3. Spanish National Cancer Research Center, Madrid, Spain
4. University of Cambridge, Cambridge, United Kingdom
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3
The Molecular and Transgenic Tools Platform at Champalimaud Foundation
Ana João Martins 1, Ana Raquel Tomás 1, Catarina Miranda 1, Hugo Lopes 1, Marta Barbosa 1, Renato Xavier 1, Ana Catarina Certal 1 1. Champalimaud Foundation, Lisbon, PT
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4
Sentinels at the Gate, Soldiers in the Tumor: Spatially Distinct CD8 T-cell Subsets Coordinate Liver Metastasis Control
Raquel L. Sequeira 1,2, Beatriz Azevedo 1,3, Helena Silva 1, Daniela Amaral-Silva 1, Negisa Toutounchi 3, Camila Veludo Ramos 1, Joke M. M. den Haan 3, Inês Ramos 1, Klaas van Gisbergen 1
1. Champalimaud Foundation, Lisbon, PT
2. Faculty of Medicine and Biomedical Sciences, University of Algarve, Faro, PT
3. Faculty of Medicine, University of Lisbon, Lisbon, PT
4. Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Netherlands, NL
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5
A Framework for Tracking the Origin and Regulation of Tumor-Fighting T cells
Daniela Amaral-Silva 1, Raquel L. Sequeira 1, Helena Silva 1, Klaas van Gisbergen 1
1. Champalimaud Foundation, Lisbon, PT
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6
Immunity-Matched cDCpoiesis: The Balance of cDC Subsets in Type 1 vs Type 2 Immunity
Miguel Â. Magalhães-Patrício 1*, Sahar S.H. Tehrani 1*, Robert W. Baber 1, Hannah S. Blumtritt 1, Mariana Henriques 1, Vasco Correia 1, Maria V. Pires 1, Kyle T. Cunningham 1, Neuza Sousa 2, Frank Brombacher 3, João C. Guimarães 4, Joana Neves 2, Pedro Sousa-Victor 2, Andreas Wack 5, Bart N. Lambrecht 6, Judith E. Allen 7, Carlos Minutti 1
* Co-first authorships
1. Champalimaud Foundation, Champalimaud Centre for the Unknown, Immunoregulation Lab, Lisbon, PT
2. Instituto Gulbenkian de Medicina Molecular, The Aging & Tissue Repair lab, Lisbon, PT
3. Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, ZA
4. Faculdade de Medicina, Universidade de Lisboa, Lisboa, PT
5. The Francis Crick Institute, Immunoregulation Lab, London, UK
6. Laboratory of Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent University, Ghent, BE
7. Faculty of Life Sciences, University of Manchester, UK
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7
Blood-Brain Barrier (BBB)-On-a-Chip: an Innovative Platform for Drug Delivery in Cancer Research
Mafalda Silva 1, Beatriz Simões 1, Marco Cavaco 1,2, Miguel Castanho 1,2, Vera Neves 1,2
1. Gulbenkian Institute for Molecular Medicine (GIMM), Lisboa, PT
2. Faculdade de Medicina, Universidade de Lisboa, Lisboa, PT
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8
Deciphering Injury-Induced Glia-Derived Signals: Local and Systemic Roles
María Victoria Canal 1, Daniela Cuffs 1, Beatriz Ferreira 1, Christa Rhiner 1.
1. Champalimaud Foundation, Lisbon, PT
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9
Extracellular Matrix Remodelling in Brain Repair and Tumoral Context
Juan Andrés Sánchez 1, Mariana B. Santos 1, Ana Cristina Ojalvo 1, Daniela Pão Alvo 1, Anabel R Simões 1, Sara Monteiro-Ferreira 1, Patricia Das Neves Borges 1, Tânia Carvalho 1, Adriana Sánchez-Danés 1, Sergio Casas-Tintó 2 and Christa Rhiner 1
1. Champalimaud Foundation, Lisbon, PT
2. Instituto de Salud Carlos III, Madrid, ES
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10
Stromal-Induced Tumor Remodeling Promotes Immune Evasion in Pancreatic Cancer
Sara Trindade-Correia 1, Manuel Jacinto 1, Maria Keridon 1, Francisco Costa 1, Helena C. Silva 1, Camila Veludo 1, Klaas van Gisbergen 1, Inês Ramos 1
Champalimaud Foundation, Lisbon, PT
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11
Tracing the Origin of Tissue Resident Memory CD8 T cells
Camila V. Ramos 1, Klaas van Gisbergen 1
1. Champalimaud Foundation, Lisbon, PT
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12
Investigating the Antigenicity of Glioblastoma Stem Cells Upon Novel Therapeutic Treatments
Megan Maloney 1, 2, 3, Constance Fourny 1, 2, Juliane Liepe 4, Keyoumars Ashkan 5, Roberta Azzarelli 3, Michele Mishto 1, 2.
1. Peter Gorer Department of Immunobiology, King’s College London, SE1 1UL London, UK.
2. The Francis Crick Institute, NW1 1AT London, UK
3. UCL School of Pharmacy, University College London, WC1N 1AX London, UK.
4. Max Planck Institute for Multidisciplinary Sciences, Quantitative and Systems Biology, 37077 Göttingen, DE
5. Department of Neurosurgery, King’s College Hospital, NHS Foundation Trust, London, UK.
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13
Characterization of Erythroblastic Islands and Their Dynamic Interactions with Acute Myeloid Leukemia Cells Using Live Imaging in Zebrafish Xenografts
Diogo Velez 1, 2, Inês Trancoso 1, Delfim Duarte 3, 4, Rita Fior 1
1. Champalimaud Foundation, Lisbon, PT
2. Faculty of Sciences, University of Lisbon, Lisbon, PT
3. Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, PT
4. Instituto Português de Oncologia do Porto Francisco Gentil (IPO Porto), Porto, PT
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14
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15
Enhancing Brain Delivery of PARP Inhibitors for Triple-Negative Breast Cancer Brain Metastases Using Blood-Brain Barrier Peptide Shuttles
M Cavaco 1,2, M Domingos 1 , R Silva 2, T Brunner 3, C Espósito 4, M Gómez 4, M Keller 3, P Koch 3, J Llop 4, V Neves 1,2, M Castanho 1,2
1. Gulbenkian Institute for Molecular Medicine (GIMM), Lisbon, PT
2. Faculdade de Medicina, Universidade de Lisboa, Lisbon, PT
3. University of Regensburg, Regensburg, DE
4. CICbiomaGUNE, Gipuzkoa, ES
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16
A Whole-Genome Screen Identifies a Bilateral Flower-Grindelwald/TNFR-Veli/LIN-7 Communication Module in Cell Competition
Catarina Marçal-Costa 1, Catarina Brás-Pereira 2, Dina Coelho 1, Sara Banazol 1, Marta Curado Avelar 1, Joana Couceiro 1, Christa Rhiner 1, Eduardo Moreno 1
1. Champalimaud Foundation, Lisbon, PT
2. Gulbenkian Institute for Molecular Medicine, Lisbon, PT
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17
Neutrophils Drive Circadian Thermogenesis in Brown Adipose Tissue
Tommaso Vicanolo 1, Beatriz Cicuendez 1, Andrea Rubio-Ponce 2, Lucia Dominguez 1, Guadalupe Sabio 1, Ivan Ballesteros 1, Andres Hidalgo 1,2
1. Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, ES
2. Vascular Biology and Therapeutics Program and Department of Immunobiology, Yale University School of Medicine, New Haven, USA
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18
PRC2 Loss Reprograms Colorectal Cancer into an Oncofetal State in Zebrafish Xenografts
Raquel Cavaco 1,2, Bruna Costa 1, Laura Solé 3,4, Lluis Espinosa 3,4, Rita Fior 1
1. Champalimaud Foundation, Lisbon, PT
2. University of Algarve, Faro, PT
3. Hospital del Mar Research Institute, Barcelona, ES
4. Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, ES
