︎
 ︎︎︎ become a partner of CRSy26 ︎︎︎ looking for a place to stay during CRSy26? take a look at our partner hotels! ︎︎︎ didn’t register? get your live streaming ticket ︎︎︎ join >270 participants from 32 countries and 32 institutions worldwide ︎︎︎ 4 keynote talks, 13 invited speakers, 7 selected talks, 2 poster sessions ︎︎︎ tours, meet the speaker, a boat trip, and a dinner party await. check the full social programme here 


 
︎  Time in Lisbon (WEST)


wednesday 14


morning chair
Ana Luísa Correia
Champalimaud Foundation
Lisbon, Portugal
afternoon chair
Adriana Sánchez-Danés
Champalimaud Foundation
Lisbon, Portugal
︎

08:30

registration & welcome coffee


︎

09:30

opening remarks


Leonor Beleza, President of the Champalimaud Foundation
Carlos Minutti and Henrique Veiga-Fernandes, Chairs of CRSy26
Champalimaud Foundation
Lisbon, Portugal



 session 1 — cancer ecosystems: nerves, vessels and the tumour microenvironment 


10:00

Douglas Hanahan, PhD

Ludwig Institute for Cancer Research
Swiss Institute for Experimental Cancer Research (ISREC)
Swiss Federal Institute of Technology Lausanne
Lausanne, Switzerland


︎

11:00

coffee break


︎

11:30
Neuroimmune Interactions in Lung Adenocaricnoma

Leanne Li, MD, PhD
The Francis Crick Institute
London, UK
︎

13:00

lunch break


︎

14:00
Posters I
︎ Click for further details

︎

15:30
coffee break


 session 2 — tumour initiation, metastasis and myeloid surveillance 



16:00
Ana Luísa Correia, PhD
Champalimaud Foundation
Lisbon, Portugal
︎

16:30
Neutrophils: Born Different, Adapted for Purpose

Lai Guan Ng, PhD
Westlake University
Hangzhou, China

︎

17:00

champalimaud tours


Get to know the inside of the Champalimaud Foundation and discover the groundbreaking science conducted within its walls.

︎  Time in Lisbon (WEST)

posters I


wednesday 14
14:00 – 15h30 

1

-


︎

2

Fishing for New Immunotherapy Compounds to Boost Innate-Tumor Rejection


Ana Beatriz Machado 1, Inês Oliveira 1, Carlos Labão-Almeida 2,3, Vanda Póvoa 1, Luís Leite 1, Domenico Calaffato 1, Beatriz Sebo 1, Cátia Rebelo de Almeida 1, Bruna Costa 1, Renata Couto 2,3, Gonçalo Bernardes 2,3,4, and Rita Fior 1

1. Champalimaud Foundation, Lisbon, Portugal
2. Gulbenkian Institute of Molecular Medicine, Lisbon, Portugal
3. Spanish National Cancer Research Center, Madrid, Spain
4. University of Cambridge, Cambridge, United Kingdom
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3

The Molecular and Transgenic Tools Platform at Champalimaud Foundation

Ana João Martins 1, Ana Raquel Tomás 1, Catarina Miranda 1, Hugo Lopes 1, Marta Barbosa 1, Renato Xavier 1, Ana Catarina Certal 1
1. Champalimaud Foundation, Lisbon, PT

︎

4

Sentinels at the Gate, Soldiers in the Tumor: Spatially Distinct CD8 T-cell Subsets Coordinate Liver Metastasis Control


Raquel L. Sequeira 1,2, Beatriz Azevedo 1,3, Helena Silva 1, Daniela Amaral-Silva 1, Negisa Toutounchi 3, Camila Veludo Ramos 1, Joke M. M. den Haan 3, Inês Ramos 1, Klaas van Gisbergen 1
1. Champalimaud Foundation, Lisbon, PT
2. Faculty of Medicine and Biomedical Sciences, University of Algarve, Faro, PT
3. Faculty of Medicine, University of Lisbon, Lisbon, PT
4. Department of Molecular Cell Biology and Immunology, Amsterdam UMC, Netherlands, NL

︎

5

A Framework for Tracking the Origin and Regulation of Tumor-Fighting T cells


Daniela Amaral-Silva 1, Raquel L. Sequeira 1, Helena Silva 1, Klaas van Gisbergen 1
1. Champalimaud Foundation, Lisbon, PT

︎

6

Immunity-Matched cDCpoiesis: The Balance of cDC Subsets in Type 1 vs Type 2 Immunity


Miguel Â. Magalhães-Patrício 1*, Sahar S.H. Tehrani 1*, Robert W. Baber 1, Hannah S. Blumtritt 1, Mariana Henriques 1, Vasco Correia 1, Maria V. Pires 1, Kyle T. Cunningham 1, Neuza Sousa 2, Frank Brombacher 3,  João C. Guimarães 4, Joana Neves 2, Pedro Sousa-Victor 2, Andreas Wack 5, Bart N. Lambrecht 6, Judith E. Allen 7, Carlos Minutti 1
* Co-first authorships
1. Champalimaud Foundation, Champalimaud Centre for the Unknown, Immunoregulation Lab, Lisbon, PT
2. Instituto Gulbenkian de Medicina Molecular, The Aging & Tissue Repair lab, Lisbon, PT
3. Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, ZA
4. Faculdade de Medicina, Universidade de Lisboa, Lisboa, PT
5. The Francis Crick Institute, Immunoregulation Lab, London, UK
6. Laboratory of Mucosal Immunology, VIB-UGent Center for Inflammation Research, Ghent University, Ghent, BE
7. Faculty of Life Sciences, University of Manchester, UK

︎

7

Blood-Brain Barrier (BBB)-On-a-Chip: an Innovative Platform for Drug Delivery in Cancer Research


Mafalda Silva 1, Beatriz Simões 1, Marco Cavaco 1,2, Miguel Castanho 1,2, Vera Neves 1,2
1. Gulbenkian Institute for Molecular Medicine (GIMM), Lisboa, PT
2. Faculdade de Medicina, Universidade de Lisboa, Lisboa, PT

︎

8

Deciphering Injury-Induced Glia-Derived Signals: Local and Systemic Roles


María Victoria Canal 1, Daniela Cuffs 1, Beatriz Ferreira 1, Christa Rhiner 1.
1. Champalimaud Foundation, Lisbon, PT

︎

9

Extracellular Matrix Remodelling in Brain Repair and Tumoral Context


Juan Andrés Sánchez 1, Mariana B. Santos 1, Ana Cristina Ojalvo 1, Daniela Pão Alvo 1, Anabel R Simões 1, Sara Monteiro-Ferreira 1, Patricia Das Neves Borges 1, Tânia Carvalho 1, Adriana Sánchez-Danés 1, Sergio Casas-Tintó 2 and Christa Rhiner 1
1. Champalimaud Foundation, Lisbon, PT
2. Instituto de Salud Carlos III, Madrid, ES

︎

10

Stromal-Induced Tumor Remodeling Promotes Immune Evasion in Pancreatic Cancer


Sara Trindade-Correia 1, Manuel Jacinto 1, Maria Keridon 1, Francisco Costa 1, Helena C. Silva 1, Camila Veludo 1, Klaas van Gisbergen 1, Inês Ramos 1
Champalimaud Foundation, Lisbon, PT

︎

11

Tracing the Origin of Tissue Resident Memory CD8 T cells


Camila V. Ramos 1, Klaas van Gisbergen 1
1. Champalimaud Foundation, Lisbon, PT

︎

12

Investigating the Antigenicity of Glioblastoma Stem Cells Upon Novel Therapeutic Treatments


Megan Maloney 1, 2, 3, Constance Fourny 1, 2, Juliane Liepe 4, Keyoumars Ashkan 5, Roberta Azzarelli 3, Michele Mishto 1, 2.
1. Peter Gorer Department of Immunobiology, King’s College London, SE1 1UL London, UK.
2. The Francis Crick Institute, NW1 1AT London, UK
3. UCL School of Pharmacy, University College London, WC1N 1AX London, UK.
4. Max Planck Institute for Multidisciplinary Sciences, Quantitative and Systems Biology, 37077 Göttingen, DE
5. Department of Neurosurgery, King’s College Hospital, NHS Foundation Trust, London, UK.

︎

13

Characterization of Erythroblastic Islands and Their Dynamic Interactions with Acute Myeloid Leukemia Cells Using Live Imaging in Zebrafish Xenografts


Diogo Velez 1, 2, Inês Trancoso 1, Delfim Duarte 3, 4, Rita Fior 1
1. Champalimaud Foundation, Lisbon, PT
2. Faculty of Sciences, University of Lisbon, Lisbon, PT
3. Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, PT
4. Instituto Português de Oncologia do Porto Francisco Gentil (IPO Porto), Porto, PT

︎

14

-


︎

15

Enhancing Brain Delivery of PARP Inhibitors for Triple-Negative Breast Cancer Brain Metastases Using Blood-Brain Barrier Peptide Shuttles


M Cavaco 1,2, M Domingos 1 , R Silva 2, T Brunner 3, C Espósito 4, M Gómez 4, M Keller 3, P Koch 3, J Llop 4, V Neves 1,2, M Castanho 1,2
1. Gulbenkian Institute for Molecular Medicine (GIMM), Lisbon, PT
2. Faculdade de Medicina, Universidade de Lisboa, Lisbon, PT
3. University of Regensburg, Regensburg, DE
4. CICbiomaGUNE, Gipuzkoa, ES

︎

16

A Whole-Genome Screen Identifies a Bilateral Flower-Grindelwald/TNFR-Veli/LIN-7 Communication Module in Cell Competition


Catarina Marçal-Costa 1, Catarina Brás-Pereira 2, Dina Coelho 1, Sara Banazol 1, Marta Curado Avelar 1, Joana Couceiro 1, Christa Rhiner 1, Eduardo Moreno 1
1. Champalimaud Foundation, Lisbon, PT
2. Gulbenkian Institute for Molecular Medicine, Lisbon, PT

︎

17

Neutrophils Drive Circadian Thermogenesis in Brown Adipose Tissue


Tommaso Vicanolo 1, Beatriz Cicuendez 1, Andrea Rubio-Ponce 2, Lucia Dominguez 1, Guadalupe Sabio 1, Ivan Ballesteros 1, Andres Hidalgo 1,2
1. Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid, ES
2. Vascular Biology and Therapeutics Program and Department of Immunobiology, Yale University School of Medicine, New Haven, USA

︎

18

PRC2 Loss Reprograms Colorectal Cancer into an Oncofetal State in Zebrafish Xenografts


Raquel Cavaco 1,2, Bruna Costa 1, Laura Solé 3,4, Lluis Espinosa 3,4, Rita Fior 1
1. Champalimaud Foundation, Lisbon, PT
2. University of Algarve, Faro, PT
3. Hospital del Mar Research Institute, Barcelona, ES
4. Centro de Investigación Biomédica en Red Cáncer (CIBERONC), Madrid, ES




︎  Time in Lisbon (WEST)

thursday 15

morning chair
Pavel Hanč
Gulbenkian Institute for Molecular Medicine (GIMM)
Lisbon, Portugal
afternoon chair
Roksana M. Pirzgalska, PhDChampalimaud Foundation
Lisbon, Portugal

︎

09:00

registration & welcome coffee



 session 3 — origins of immunity: haematopoiesis, lineage decisions and memory 



09:30
keynote lecture
T Cells on My Mind and in My Mind

Susan Kaech, PhD

Allen Institute
Seattle, Washington, USA


︎

10:30

Adaptive and Maladaptive Myeloid Cell Production


Emmanuelle Passegué, PhD
Columbia University Irving Medical Center
New York, New York, USA

︎

11:00

coffee break


︎

11:30
Noradrenergic Control of cDC2A Progenitor Output in the Bone
Marrow

Carlos Minutti, PhD
Champalimaud Foundation
Lisbon, Portugal

︎

13:00

lunch break


︎

14:00

Posters II

︎ Click for further details

︎

15:30

coffee break



 session 4 — innate immune programming in tissues and tumours 



︎

16:15

︎

16:45

group photo

A moment for the CRSy26 history books. Join us for the official group photo.


︎

17:00

meet the speaker


Join us for a relaxed cocktail to mingle with CRSy26's keynotes and invited speakers, and network with peers from across the field.
︎  Time in Lisbon (WEST)

posters II

thursday 15
14:00 – 15h30 



1

-


︎

2

A Verifiable Trust Framework for Collaborative AI Research in Neuro-Immune Oncology


Jacob Ninan 1
1. Kottackal Business Solutions, Thiruvananthapuram, IN

︎

3

Deciphering Pulmonary Neuron-ILC Communication


Ana Rasteiro 1*, Maria Aliseychik 1*, Bruno Raposo 1, Henrique Veiga-Fernandes 1
1. Champalimaud Research, Champalimaud Foundation, Lisbon, PT

︎

4

Mapping the Central Nervous System Response to Th1 and Th2 Immune Profiles


Maria Aliseychik 1*, Ana Rasteiro 1*, Bruno Raposo 1, Henrique Veiga-Fernandes 1
1. Champalimaud Research, Champalimaud Centre for the Unknown, Lisbon, PT

︎

5

In Vitro Evaluation of Innovative Peptides Towards Breast Cancer Metastization


Ana Estrela 1,2, Marco Cavaco 1,3, Miguel A.R.B. Castanho 1,3
1. Gulbenkian Institute for Molecular Medicine (GIMM), Lisboa, PT
2. Faculdade de Ciências, Universidade de Lisboa, Lisboa, PT
3. Faculdade de Medicina, Universidade de Lisboa Universidade de Lisboa, Lisboa, PT

︎

6

Exercise as an Immune Modulator: Early Findings from a Mouse Model


Maria Casquinha 1,2,3, Tatiana J. Carneiro 2, Júlio A. Torres 1,2,3, Tomás Oliveira-Machado 1,2,3, Ana R. Matias 2, Maria Vieira 2, Diana Correia 2, Sofia Cunha 2, Manuela Ferreira 2
1. University of Coimbra, Institute for Interdisciplinary Research, Coimbra, PT
2. University of Coimbra, Center for Innovative Biomedicine and Biotechnology, Center for Neuroscience and Cell Biology, Coimbra, PT
3. University of Coimbra, Institute of Interdisciplinary Research, Doctoral Programme in Experimental Biology and Biomedicine, Coimbra, PT

︎

7

The Champalimaud Fish Platform: Integrated Services and Cryopreservation Solutions for Fish-Based Biomedical Research


Guilherme Antunes 1, Joana Monteiro 1, Inês Oliveira 1, Pedro Seco 1, Dionísio Sousa 1, Vanessa Pinto 1, Mariana Salvador 1, Ana Catarina Certal 1
1. Champalimaud Foundation, Lisbon, PT

︎

8

Retinoic Acid Modulates Invariant Natural Killer T Cell Development
and Function in Colon Cancer


Tomás Oliveira-Machado 1,5; Diana Correia 1,6; Sílvia Madeira Arroz 2; Ana Raquel Silva 3; Patricia Bastos-Amador 3; Bruno Raposo 3; Afonso R. M. Almeida 4; Hélder Ribeiro 3; Henrique Veiga-Fernandes 3; Manuela Ferreira 1
1. University of Coimbra, Center for Innovative Biomedicine and Biotechnology, Center for Neuroscience and Cell Biology, 3004-504, Coimbra, PT
2. Department of Oncology, University of Lausanne, CH
3. Champalimaud Foundation, Lisbon, PT
4. Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina, Universidade de Lisboa, Lisboa, PT
5. University of Coimbra, Institute for Interdisciplinary Research, Doctoral Programme in Experimental Biology and Biomedicine (PDBEB), Portugal;
6. Faculty of Medicine, University of Coimbra, Master Program in Biomedical Research (MIB), Coimbra, PT

︎

9

Stromal Clearance of Dying Cells: a Novel Mechanism of Immune Evasion in Pancreatic Cancer


Daniela Guedes 1, Thi Thao Nguyen Phan 1, Amber de Nooij 1, Klaas Van Gisbergen 1, Inês Ramos 1
1. Champalimaud Foundation, Lisbon, PT

︎

10

Classpose: Automatic Whole Slide Image-Scale Cell Phenotyping in H&E Uncovers Spatial-Morphological Signatures in Colorectal Cancer


José Guilherme de Almeida 1, Soham Mandal 2,3, Konstantin Bräutigam 3,4, Trevor A Graham2, Nickolas Papanikolaou1 5
1. Champalimaud Foundation, PT
2. Data Science Team, Institute of Cancer Research, London, UK
3. Centre for Evolution and Cancer, Institute of Cancer Research, London, UK
4. Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, CH
5. Royal Marsden Hospital, Sutton, UK

︎

11

Radiomics Show Promise for the Identification of Invisible Prostate Cancer Lesions


Ana Sofia de Castro Verde 1,2, José Guilherme de Almeida 1, Alexandre Calado 1, Maria José Brito 3, Paulo Santos Correia 4, Adolfo Firpo-Betancourt 3, Jorge Fonseca 5, Celso Matos 4, Raquel Cruz Conceição 2, Nickolas Papanikolaou 1
1. Computational Clinical Imaging Group, Champalimaud Foundation, Lisbon, PT
2. Instituto de Biofísica e Engenharia Biomédica, Faculdade de Ciências da Universidade de Lisboa, Lisbon, PT
3. Anatomical Pathology Unit, Champalimaud Foundation, Lisbon, PT
4. Radiology Department, Champalimaud Foundation, Lisbon, PT
5. Urology Unit, Champalimaud Foundation, Lisbon, PT

︎

12

The Transcription Factor Hobit Distinguishes Canonical From Exhausted Like Resident Memory CD8+T Cells Arising in Lungs After Influenza Infection


Germano Teixeira Vicente 1, Lynn Vermeer, Helena C. Silva 1, Natasja Kragten 2, Camila V. Ramos, Champalimaud Foundation 1, Klaas van Gisbergen 1
1. Champalimaud Foundation, Lisbon, PT
2. Sanquin Blood Supply Foundation, Amsterdam, NL

︎

13

Spatial Profiling of Tissue-Guided Adaptation of cd8⁺ T-cells in Metastatic Breast Cancer


Beatriz Azevedo 1,2, Raquel L. Sequeira 1, Camila Veludo Ramos 1, Helena Silva 1, Inês Ramos 1, Klaas van Gisbergen 1
1. Champalimaud Foundation, Lisbon, PT
2. Faculty of Medicine, University of Lisbon, Lisbon, PT

︎

14

Single-Cell RNA-Seq of the Injured Optic Lobes Reveals Potential Glial Targets in Brain Repair


Arjun Aji Reeja 1, Ana Cristina Ojalvo-Sanz 1,2, Carolina Alves 1, Christa Rhiner 1
1. Champalimaud Foundation, Lisbon, PT
2. Cajal Neuroscience Centre (CNC-Ci2A-CSIC), Madrid, ES

︎

15

Integrated Blood-Brain Barrier and Brain Metastasis Models for Peptide-Drug Conjugates Validation


Joana Ratado 1,2, Marco Cavaco 2,3, Miguel Castanho 2,3, Ana Coutinho 1, Vera Neves 2,3
1. Faculdade de Ciências, Universidade de Lisboa, Lisbon, PT
2. Gulbenkian Institute for Molecular Medicine (GIMM), Lisbon, PT
3. Faculdade de Medicina, Universidade de Lisboa, Lisbon, PT

︎

16

Dietary Fatty Acid Identity Shapes Myelopoiesis and Macrophage Function


Juan M. Lozano-Gil 1, Maria V. Pires 1, Carlos M. Minutti 1
1. Champalimaud Foundation, Lisbon, PT

︎

17

Neuroendocrine Regulation of Type 2 Immune Responses in Health and Disease


Cristina Godinho-Silva 1, Miguel Rendas 1, Bruno Raposo 1, David Brea 2, Rita G. Domingues 3, Hélder Ribeiro 1, Inês Godinho 1, Henrique Veiga-Fernandes 1
1. Champalimaud Foundation, Lisbon, PT
2. Institute of Biomedical Research of Barcelona, Barcelona, ES
3. Lydia Becker Institute of Immunology and Inflammation, University of Manchester, Manchester, UK

︎

18

Homeostatic Integration of Reward and Toxicity Shapes Neural Computation and Adaptive Behavior


Salar Nouri 1, Yunhan Hao 2, Pakhi Banchalia 2, Harikrishna Satheesh Pillai 2, Naoto Yoshida 3, Roxana Zeraati 4, Shervin Safavi 4, 5
1. Frankfurt Institute for Advanced Studies, Frankfurt, DE 
2. Department of Computer Science, Technische Universität Dresden, Dresden, DE
3. Graduate School for Informatics, Kyoto University, Kyoto, JP
4. Department of Computational Neuroscience, Max Planck Institute for Biological Cybernetics, Tübingen, DE
5. Computational Neuroscience, Department of Child and Adolescent Psychiatry, Faculty of Medicine, Technische Universität Dresden, Dresden, DE